Abstract

The incidence of multidrug-resistant tuberculosis (MDR-TB) is on the rise globally. MDR-TB takes a minimum of 2 years to treat and the treatment regimen produces many adverse drug reactions (ADRs). The World Health Organization (WHO) has called for further research on the treatment of community- based MDR-TB patients as care is being decentralized to outpatient settings. In the WHO's TB progress report for 2015, they note there is a dearth of literature about anti- TB drug-induced mortality, morbidity and loss in quality of life, particularly in low- resource settings.

This study directly addresses this gap in knowledge by examining the effect of ADRs from MDR-TB treatment on heath-related quality of life (HRQOL) for patients in a low-resource, high HIV-burden population in South Africa.

Ana Maria Kelly

Author Details

Ana Maria Kelly, PhD, RN

Sigma Membership

Alpha Psi

Type

Dissertation

Format Type

Text-based Document

Study Design/Type

Cross-Sectional

Research Approach

Quantitative Research

Keywords:

Mycobacterium Tuberculosis, Mycobacterium Tuberculosis Drug Effects, Multidrug resistant Epidemiology, Multidrug Resistant Prevention and Control, Anti HIV Agents Adverse Effects, South Africa

Advisor

Barbara Smith

Degree

PhD

Degree Grantor

Michigan State University

Degree Year

2015

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Self-submission

Date of Issue

2015-10-02

Full Text of Presentation

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