Abstract
Traumatic brain injury (TBI) affects 1.7 million Americans annually leading to significant morbidity and health care costs. An important cause of morbidity in TBI is secondary brain injury due to abnormal cerebrovascular autoregulation (CA). Standard measures of CA are not amenable to use outside of the intensive care unit (ICU) and patients continue to be at risk for secondary brain injury post- ICU. Baroreflex sensitivity (BRS) is a non-invasive assessment of autonomic tone that may be useful in evaluating CA. Evaluation of BRS and its relation to CA has not been examined in patients with TBI and predictors of CA are unknown.
The specific aims for this study were to (1) examine the association between BRS and CA in patients with TBI, (2) compare BRS and CA in TBI patients and age and gender matched healthy volunteers (HV) and (3) identify predictors of BRS and CA in TBI.
Sigma Membership
Delta Mu, Gamma Mu
Type
Dissertation
Format Type
Text-based Document
Study Design/Type
Quasi-Experimental Study, Other
Research Approach
Quantitative Research
Keywords:
Neurology Patients, Intensive Care Patients, Inpatients
Advisor
Mary A. Woo
Degree
PhD
Degree Grantor
University of California, Los Angeles
Degree Year
2012
Recommended Citation
McNair, Norma D., "Baroreflex sensitivity during positional changes in patients with traumatic brain injury" (2020). Dissertations. 1195.
https://www.sigmarepository.org/dissertations/1195
Rights Holder
All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.
All permission requests should be directed accordingly and not to the Sigma Repository.
All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
Review Type
None: Degree-based Submission
Acquisition
Proxy-submission
Date of Issue
2020-07-10
Full Text of Presentation
wf_yes
Description
This dissertation has also been disseminated through the ProQuest Dissertations and Theses database. Dissertation/thesis number: 3511290; ProQuest document ID: 1022495550. The author still retains copyright.