Abstract

The purpose of this study was to evaluate potential relationships between perinatal dexamethasone treatment of premature infants and latent child development. Often, postnatal corticosteroid (PNS) is offered in the neonatal intensive care unit (NICU) to wean mechanical ventilation. Experts suggested minimizing PNS use after studies identified higher milligrams per kilogram (mg/kg) as a risk factor for adverse developmental outcomes. This study quantified fetal dexamethasone and cumulative perinatal dexamethasone by mg/kg exposure to accurately assess associations between steroid exposure and premature infant behavioral development.

Description

This dissertation has also been disseminated through the ProQuest Dissertations and Theses database. Dissertation/thesis number: 3142536; ProQuest document ID: 305201585. The author still retains copyright.

Author Details

Isabell Biene Purdy, PhD, NNP, CPNP, Emeritus Professor

Sigma Membership

Gamma Tau at-Large

Type

Dissertation

Format Type

Text-based Document

Study Design/Type

Cohort

Research Approach

Other

Keywords:

Corticosteroids, Child Development, Perinatal Treatment, Premature Infants, Perinatal Dexamethasone Treatements

Advisor

Dorothy J. Wiley

Second Advisor

Lina Bader

Third Advisor

Anna Gawlinski

Fourth Advisor

Lynne Smith

Degree

PhD

Degree Grantor

University of California, Los Angeles

Degree Year

2004

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Proxy-submission

Date of Issue

2021-12-21

Full Text of Presentation

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