Abstract

Compelling evidence exists for the role of supraspinal centers in the modulation of nociception. For example, numerous studies have established that stimulation of the spinally-projecting serotonergic neurons in the ventromedial medulla (VMM) inhibits nociception. Several sites within the brainstem are known to innervate the VMM, including the periaqueductal gray (PAG) as well as other sites. Experiments performed in our laboratory have demonstrated that some neurons in the dorsolateral pontine tegmentum (DLPT) have dense projections to the VMM and appear to modulate nociception. The purpose of this research was to investigate the anatomical and functional role of these projections from the DLPT to the VMM.

Description

This dissertation has also been disseminated through the ProQuest Dissertations and Theses database. Dissertation/thesis number: 9310104; ProQuest document ID: 304005608. The author still retains copyright.

Author Details

Judith Ann Paice, PhD, RN, FAAN

Sigma Membership

Gamma Phi

Type

Dissertation

Format Type

Text-based Document

Study Design/Type

Other

Research Approach

Other

Keywords:

Pain Perception, Neural Pathways, Neurology

Advisor

Felissa Cohen

Degree

PhD

Degree Grantor

University of Illinois Chicago

Degree Year

1992

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Proxy-submission

Date of Issue

2019-05-06

Full Text of Presentation

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