Abstract
When a patient is exposed surgical stress, the endocrine system secretes hormones in response to that stress. These hormones further activate the immune system to release cytokines and other acute phase reactions. These processes are supposed to protect the body by upregulating the innate immune system and producing an inflammatory response that acts to protect and heal. However, uncontrolled surgical stress may cause a weaker immune response that may lead to delayed wound healing. The phenomenon of unplanned perioperative hypothermia is known to expose patients to additional surgical stress. The purpose of this preliminary experimental study was to determine the effect of a preoperative warming intervention on the acute phase response of surgical stress in surgical patients. Specifically, the aim of this study was to evaluate the effect of a prewarming intervention using a forced-air warming (FAW) device versus routine care (RC) using warmed cotton blankets on the development of unplanned hypothermia, cytokine production, and endocrine responses. It was hypothesized that (1) the FAW participants would experience less unplanned perioperative hypothermia than the RC participants; (2) the FAW participants would experience lower catecholamine and cortisol levels than the RC participants; and (3) the FAW participants would experience higher proinflammatory cytokine and CRP production intra- and postoperatively than the RC participants.
Sigma Membership
Mu Phi at-Large
Type
Dissertation
Format Type
Text-based Document
Study Design/Type
Randomized Controlled Trial
Research Approach
Pilot/Exploratory Study
Keywords:
Forced-Air Warming, Stress Relief, Surgical Patients
Advisor
Maureen Groer
Degree
PhD
Degree Grantor
University of South Florida
Degree Year
2007
Recommended Citation
Wagner, Vanda Doreen, "Effect of a preoperative warming intervention on the acute phase response of surgical stress" (2020). Dissertations. 187.
https://www.sigmarepository.org/dissertations/187
Rights Holder
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All permission requests should be directed accordingly and not to the Sigma Repository.
All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
Review Type
None: Degree-based Submission
Acquisition
Proxy-submission
Date of Issue
2020-01-06
Full Text of Presentation
wf_yes
Description
This dissertation has also been disseminated through the ProQuest Dissertations and Theses database. Dissertation/thesis number: 3306842; ProQuest document ID: 304819228. The author still retains copyright.