Abstract
The aims of this dissertation study were: [First part of the dissertation study] 1. To explore the relationships among fatigue and co-occurring symptoms (i.e., abdominal pain, depression and anxiety). (1-a) the relationships between abdominal pain and fatigue; and (1-b) whether psychological distress (i.e., depression and anxiety) mediates the effect of abdominal pain on fatigue, across-women and within-woman; and [Second part of the dissertation study] 2. To determine (2-a) if latent classes (i.e. subgroups) of women with IBS could be identified based on the symptom cluster severity of fatigue, abdominal pain, depression and anxiety, (2-b) if these latent classes differed on patient characteristics, and (2-c) if genetic polymorphisms of tryptophan hydroxylase (TPH), serotonin reuptake transporter (SERT) and catecholamine methyl-O-transferase (COMT) are associated with fatigue, and (2-d) with latent class membership.
Sigma Membership
Psi at-Large
Type
Dissertation
Format Type
Text-based Document
Study Design/Type
Descriptive/Correlational
Research Approach
Quantitative Research
Keywords:
Irritable Bowel Syndrome (IBS), Symptom Management, Fatigue
Advisor
Monica Jarrett
Degree
PhD
Degree Grantor
University of Washington
Degree Year
2016
Recommended Citation
Han, Claire Jungyoun, "Fatigue and co-occurring symptoms in women with irritable bowel syndrome" (2020). Dissertations. 801.
https://www.sigmarepository.org/dissertations/801
Rights Holder
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Review Type
None: Degree-based Submission
Acquisition
Proxy-submission
Date of Issue
2020-11-10
Full Text of Presentation
wf_yes
Description
This dissertation has also been disseminated through the ProQuest Dissertations and Theses database. Dissertation/thesis number: 10138866; ProQuest document ID: 1804922862. The author still retains copyright.