Abstract

The aims of this...study were: 1. To explore the relationships among fatigue and co-occurring symptoms (i.e., abdominal pain, depression and anxiety). (1-a) the relationships between abdominal pain and fatigue; and (1-b) whether psychological distress (i.e., depression and anxiety) mediates the effect of abdominal pain on fatigue, across-women and within-woman; and 2. To determine (2-a) if latent classes (i.e. subgroups) of women with IBS could be identified based on the symptom cluster severity of fatigue, abdominal pain, depression and anxiety, (2-b) if these latent classes differed on patient characteristics, and (2-c) if genetic polymorphisms of tryptophan hydroxylase (TPH), serotonin reuptake transporter (SERT) and catecholamine methyl-O-transferase (COMT) are associated with fatigue, and (2-d) with latent class membership.

Description

Dr. Han was the recipient of a Sigma Foundation for Nursing Grant.

Author Details

Claire Jungyoun Han, PhD, RN

Sigma Membership

Psi at-Large

Type

Report

Format Type

Text-based Document

Study Design/Type

Cross-Sectional

Research Approach

Quantitative Research

Keywords:

Symptoms, Cluster Analysis, Latent Profile Analysis, Women's Health, IBS, IBS and Fatigue

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Sigma Grant Recipient Report

Acquisition

Self-submission

Date of Issue

2017-04-17

Full Text of Presentation

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Grant Report

Additional Files

Abstract.pdf (68 kB)

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