Abstract
Objective: To compare the safety and efficacy of chlorhexidine versus Listerine in perioperative and intensive care settings in preventing ventilator-acquired pneumonia (VAP).
Methods: An integrative review using a keyword search was conducted in Cochrane, Cinahl, and Google Scholar databases. Data was collected regarding the efficacy of chlorhexidine and Listerine in preventing ventilator-acquired pneumonia, safety and side effect profiles, and in vivoin vitro secondary outcome measures.
Results: Chlorhexidine demonstrates superiority to Listerine in reducing ventilator-acquired pneumonia. Secondary in vivo tests including plaque and gingivitis reduction, and in vitro tests measuring the effect on bacterial loads, also favors chlorhexidine over Listerine. Chlorhexidine has shown to have significantly more side effects compared to Listerine.
Conclusions: Chlorhexidine is justifiably used in preventing ventilator-acquired pneumonia over Listerine. There is a gap in knowledge due to the lack of randomized-controlled trials utilizing Listerine in VAP bundles. Future research should focus on finding an alternative mouthwash to chlorhexidine that is equally effective at reducing VAP incidence, but lacks chlorhexidine's undesirable side effect profile.
Sigma Membership
Non-member
Type
Other Graduate Paper
Format Type
Text-based Document
Study Design/Type
Literature Review
Research Approach
Translational Research/Evidence-based Practice
Keywords:
Listerine, Ventilator-Acquired Pneumonia, Perioperative Care
Advisor
Pecka, Shannon
Degree
Doctoral-Other
Degree Grantor
Bryan College of Health Sciences
Degree Year
2018
Recommended Citation
Clements, James Owen, "Efficacy of chlorhexidine versus Listerine perioperative mouthwash in preventing ventilator-acquired pneumonia: An integrative review" (2024). Group: Bryan College of Health Sciences Doctor of Nurse Anesthesia Practice (DNAP) Collection. 4.
https://www.sigmarepository.org/group_bryan_dnap/4
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Review Type
Faculty Approved: Degree-based Submission
Acquisition
Proxy-submission
Full Text of Presentation
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