Abstract

Despite the lack of compelling evidence to support long-term efficacy in the treatment of opioid abuse, opioids are one of the most common classes of medications prescribed in the United States. As such, the significant increase in prescription and illicit opioid abuse since the nineties has led to a surge in patients recovering from addiction and now maintained on opioid replacement therapy (ORT). Due to this rapid growth in ORT, there has been a strong interest in utilization of opioid agonists such as methadone, and partial agonists such as buprenorphine, which have been increasingly utilized to treat severe chronic pain and to prevent withdrawal symptoms in those who have an addiction to opiates. The growth of this patient population has presented anesthesia providers with a challenge. Specifically, these medications interfere with the usual effect of opioids anesthesia providers use to deliver anesthesia and treat acute pain. Understanding the pharmacodynamics of the individual ORT medications prescribed is critical in terms of using the best practices to control pain in the perioperative setting. Additionally, it is imperative to communicate with all members of the healthcare team and to have a plan for managing acute perioperative pain.

Meghan Boer

Author Details

Meghan Boer, DNAP, CRNA

Sigma Membership

Non-member

Type

Other Graduate Paper

Format Type

Text-based Document

Study Design/Type

N/A

Research Approach

N/A

Keywords:

Opioid Use Disorder, Opioid Replacement Therapy, Pain Therapy, Anesthesia, Analgesics

Advisor

Hadenfeldt, Sharon

Degree

Doctoral-Other

Degree Grantor

Bryan College of Health Sciences

Degree Year

2017

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Review Type

Faculty Approved: Degree-based Submission

Acquisition

Proxy-submission

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