Abstract

Mast cell activation syndrome (MCAS) is a disorder that has only gained recognition in the past twelve years. Patients that are diagnosed with MCAS are plagued with abnormal acute and/or chronic mild to severe (anaphylaxis) mast cell activation (MCA) symptoms that affect two of four organ systems. Abnormal MCA has varying pathophysiology and is categorized as primary, secondary, or idiopathic. While similar in outcome, the prevention of MCA and medical management will vary by the subset of MCAS. This journal course reviews the pathophysiology behind MCAS and MCA. Different subclasses and treatment options of MCAS are clarified. Lastly, the anesthetic management for surgical MCAS patients is discussed.

Authors

Candace Glasgow

Author Details

Candace Glasgow, DNAP, CRNA

Sigma Membership

Non-member

Type

Other Graduate Paper

Format Type

Text-based Document

Study Design/Type

Literature Review

Research Approach

Translational Research/Evidence-based Practice

Keywords:

Mast Cell Activation Syndrome, Anesthesia, Trigger Aviodance

Advisor

Pecka, Shannon

Degree

Doctoral-Other

Degree Grantor

Bryan College of Health Sciences

Degree Year

2023

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Review Type

Faculty Approved: Degree-based Submission

Acquisition

Proxy-submission

Full Text of Presentation

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