Abstract
Aims and Objectives: The aim of this integrative review is to analyze the effects of intrathecal administration of lidocaine and bupivacaine on transient neurologic symptoms (TNS).
Methods: A review of the literature was performed utilizing the following electronic databases: Ebsco, Medline, Pubmed, CINAHL Complete, and Cochrane Complete. Search results were critically appraised based on study method and design that aligned with this integrative review's guiding questions.
Results: The use of lidocaine is associated with an increased risk of TNS when compared to other local intrathecal medications. The specific etiology of TNS remains unknown. This review revealed several contributing factors to the development of TNS. These factors include dosage and concentration of local medication, patient positioning, the type of needle used with intrathecal medication administration, and onset of ambulation after spinal anesthesia.
Conclusions: Intrathecal lidocaine is associated with an increased risk of TNS when compared to bupivacaine. Bupivacaine has a lower associated risk of TNS. Bupivacaine's drug profile, when compared to lidocaine, is correlated with longer motor recovery, increased incidence of urinary retention, and delayed discharge times. These factors are undesirable in a fast-paced, quick turnover environment.
Sigma Membership
Non-member
Type
Other Graduate Paper
Format Type
Text-based Document
Study Design/Type
Literature Review
Research Approach
Translational Research/Evidence-based Practice
Keywords:
Transient Neurologic Symptoms, Intrathecal Anesthesia, Spinal Anesthesia, Lidocaine, Bupivacaine
Advisor
Pecka, Shannon
Degree
Doctoral-Other
Degree Grantor
Bryan College of Health Sciences
Degree Year
2023
Recommended Citation
Brightweiser, Ellen, "An integrative review: The incidence of transient neurologic symptoms with the administration of intrathecal lidocaine or bupivacaine" (2024). Group: Bryan College of Health Sciences Doctor of Nurse Anesthesia Practice (DNAP) Collection. 53.
https://www.sigmarepository.org/group_bryan_dnap/53
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Rights Holder
All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.
All permission requests should be directed accordingly and not to the Sigma Repository.
All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
Review Type
Faculty Approved: Degree-based Submission
Acquisition
Proxy-submission
Full Text of Presentation
wf_yes