Abstract

Aims and Objectives: The aim of this integrative review is to analyze the effects of intrathecal administration of lidocaine and bupivacaine on transient neurologic symptoms (TNS).

Methods: A review of the literature was performed utilizing the following electronic databases: Ebsco, Medline, Pubmed, CINAHL Complete, and Cochrane Complete. Search results were critically appraised based on study method and design that aligned with this integrative review's guiding questions.

Results: The use of lidocaine is associated with an increased risk of TNS when compared to other local intrathecal medications. The specific etiology of TNS remains unknown. This review revealed several contributing factors to the development of TNS. These factors include dosage and concentration of local medication, patient positioning, the type of needle used with intrathecal medication administration, and onset of ambulation after spinal anesthesia.

Conclusions: Intrathecal lidocaine is associated with an increased risk of TNS when compared to bupivacaine. Bupivacaine has a lower associated risk of TNS. Bupivacaine's drug profile, when compared to lidocaine, is correlated with longer motor recovery, increased incidence of urinary retention, and delayed discharge times. These factors are undesirable in a fast-paced, quick turnover environment.

Author Details

Ellen Brightweiser, DNAP, CRNA

Sigma Membership

Non-member

Type

Other Graduate Paper

Format Type

Text-based Document

Study Design/Type

Literature Review

Research Approach

Translational Research/Evidence-based Practice

Keywords:

Transient Neurologic Symptoms, Intrathecal Anesthesia, Spinal Anesthesia, Lidocaine, Bupivacaine

Advisor

Pecka, Shannon

Degree

Doctoral-Other

Degree Grantor

Bryan College of Health Sciences

Degree Year

2023

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Review Type

Faculty Approved: Degree-based Submission

Acquisition

Proxy-submission

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