Abstract

Mitigating pain in early life may prevent epigenetic changes that increase an individual"s susceptibility for developing chronic pain. Adverse effects and the quality of the DNA collected challenge the suitability of saliva-extracted DNA. Saliva-extracted DNA is a feasible, noninvasive DNA sampling technique for examining OPRM1 gene methylation in preterm infants.

Author Details

Linda A. Hatfield, PhD, NNP-BC, FAAN, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Rebecca K. Hoffman, PhD, Laboratory of Innovative and Translational Nursing Research, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA

Sigma Membership

Unknown

Lead Author Affiliation

University of Pennsylvania, Philadelphia, Pennsylvania, USA

Type

Presentation

Format Type

Text-based Document, Video Recording

Study Design/Type

N/A

Research Approach

N/A

Keywords:

Saliva-extracted DNA, Gene Methylation, Preterm Infants

Conference Name

31st International Nursing Research Congress

Conference Host

Sigma Theta Tau International

Conference Location

Virtual Event

Conference Year

2020

Video/Audio Streaming

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Acquisition

Proxy-submission

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Saliva-extracted DNA is a noninvasive sampling technique for examining OPRM1 gene methylation in preterm infants

Virtual Event

Mitigating pain in early life may prevent epigenetic changes that increase an individual"s susceptibility for developing chronic pain. Adverse effects and the quality of the DNA collected challenge the suitability of saliva-extracted DNA. Saliva-extracted DNA is a feasible, noninvasive DNA sampling technique for examining OPRM1 gene methylation in preterm infants.