Abstract

The patient in the case study presents with diagnosed pulmonary hypertension (PH). Patients experiencing daily hypoxia from obstructive sleep apnea (OSA) have similar pulmonary vascular remodeling found in pulmonary hypertension patients creating pulmonary hypertension. Common to the induction of anesthesia is episodic hypotension. When the patient with PH or OSA are administered phenylephrine for hypotension, the non-specific systemic vasoconstriction will worsen PH. Vasopressin will increase systemic vascular resistance while decreasing pulmonary vascular resistance and right ventricular afterload. Vasopressin should be considered as a first-line agent in the patient with PH or OSA experiencing perioperative hypotension.

Author Details

Braden Clark, BSN, SRNA and Nancy Westbrook, DNP, MSNA, CRNA, FNP-BC, Col (Ret) USAF

Sigma Membership

Unknown

Lead Author Affiliation

Samford University, Birmingham, Alabama, USA

Type

DNP Capstone Project

Format Type

Text-based Document

Study Design/Type

Case Study/Series

Research Approach

Translational Research/Evidence-based Practice

Keywords:

Pulmonary Hypertension, Obstructive Sleep Apnea, Phenylephrine, Vasopressin, Anesthesia

Advisor

Westbrook, Nancy

Second Advisor

Herbinger, Lisa

Degree

DNP

Degree Grantor

Samford University

Degree Year

2024

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Self-submission

Date of Issue

2024-01-16

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