Abstract

Ketamine is a unique anesthetic agent with both anesthetic and analgesic properties. Ketamine is primarily a N-Methyl-D-Aspartic acid (NMDA) antagonist that also works on glutamine, nicotinic, muscarinic, monoaminergic and opioid receptors. The uses of ketamine are numerous and include treatment of chronic pain, acute pain, depression, as a multimodal pain adjunct, opioid-sparing agent and as an adjunct in enhanced recovery after surgery (ERAS) protocols.

Author Details

Michaela Wilcox, DNP (c), RN; Nancy Westbrook, DrNP, MSNA, CRNA, FNP, Col (Ret) USAF; Terri Cahoon, DNP, CRNA

Sigma Membership

Non-member

Lead Author Affiliation

Samford University, Birmingham, Alabama, USA

Type

DNP Capstone Project

Format Type

Text-based Document

Study Design/Type

Other

Research Approach

Translational Research/Evidence-based Practice

Keywords:

Ketamine, Multimodal Analgesia, Opioid-sparing

Advisor

Westbrook, Nancy Ann

Second Advisor

Cahoon, Terri

Degree

DNP

Degree Grantor

Samford University

Degree Year

2021

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Proxy-submission

Date of Issue

2021-03-24

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