Abstract

Early-Onset Neonatal Sepsis (EONS) is the leading cause of neonatal mortality and morbidity occurring in the first seven days of life. Symptoms usually develop within 12-24 hours after birth. Maternal chorioamnionitis, usually caused by Group B Streptococcus or Escherichia coli presents the greatest risk for development of EONS. Healthcare professionals are challenged with identification, management, and treatment of infants exposed to maternal chorioamnionitis while decreasing the unintended consequences of antibiotic use, including toxicity and antimicrobial resistance. Evidence demonstrates timely initiation of antibiotics reduces morbidity and mortality in infants with infections such as sepsis. However, clinicians prescribe antibiotics inappropriately or unnecessarily 20-50% of the time. Interprofessional collaboration is a key factor in improving patient outcomes. Measures to increase antibiotic stewardship requires a multilayered interprofessional approach in implementation of policies and procedures to guide physicians, nurses, and pharmacists.

Wendi Gines

Author Details

Wendi Gines, DNP, RN

Sigma Membership

Delta Alpha at-Large

Lead Author Affiliation

Samford University, Birmingham, Alabama, USA

Type

DNP Capstone Project

Format Type

Text-based Document

Study Design/Type

Quality Improvement

Research Approach

N/A

Keywords:

Maternal Chorioamnionitis, Early-onset Neonatal Sepsis, Antimicrobial Stewardship

Advisor

Buckner, Ellen

Degree

DNP

Degree Grantor

Samford University

Degree Year

2020

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Proxy-submission

Date of Issue

2020-07-17

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