Abstract

Preoperative anxiety can influence postoperative anxiety, pain, and length of stay. Short-acting benzodiazepines, such as midazolam, are routinely given preoperatively to facilitate anxiolysis and reduce anesthetic and analgesic dose requirements. Benzodiazepines can also be associated with serious side effects, such as bradypnea, apnea, and airway collapse. Melatonin is a natural neurotransmitter known to have sedative, anxiolytic, and possibly, analgesic effects. Exogenous melatonin may present a suitable alternative to benzodiazepines without unwanted side effects. In patients aged 18 and older, how does the preoperative administration of melatonin, compared to benzodiazepines, affect anxiolysis, analgesia, and anesthesia requirements perioperatively?

Author Details

Graham Herndon, BSN; Maria Ledbetter, DNAP, CRNA; Terri Cahoon, DNP, CRNA

Sigma Membership

Non-member

Lead Author Affiliation

Samford University, Birmingham, Alabama, USA

Type

DNP Capstone Project

Format Type

Text-based Document

Study Design/Type

Case Study/Series

Research Approach

Translational Research/Evidence-based Practice

Keywords:

Melatonin, Anxiolysis, Preoperative Anxiety

Advisor

Ledbetter, Maria

Degree

DNP

Degree Grantor

Samford University

Degree Year

2024

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

All permission requests should be directed accordingly and not to the Sigma Repository.

All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Self-submission

Date of Issue

2024-01-30

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